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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD1
All Species:
16.36
Human Site:
S611
Identified Species:
24
UniProt:
Q13393
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13393
NP_001123553.1
1074
124184
S611
F
K
L
F
H
P
S
S
E
S
E
Q
G
L
T
Chimpanzee
Pan troglodytes
XP_526380
1125
128795
I669
N
A
D
S
I
S
S
I
D
S
T
S
N
T
G
Rhesus Macaque
Macaca mulatta
XP_001085464
1074
124020
S611
F
K
L
F
R
P
S
S
E
S
E
Q
G
L
T
Dog
Lupus familis
XP_545291
1075
123911
S612
L
K
L
F
R
S
S
S
K
S
E
Q
G
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z280
1074
123950
S611
L
K
L
F
H
P
S
S
E
S
E
Q
G
L
T
Rat
Rattus norvegicus
P70496
1074
123795
S611
L
K
L
F
R
P
S
S
E
S
E
Q
G
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513744
295
33781
Chicken
Gallus gallus
XP_422793
1072
123414
H610
L
R
M
F
L
H
L
H
S
E
S
Q
G
S
W
Frog
Xenopus laevis
NP_001129642
1039
119219
I583
H
A
D
S
V
S
S
I
D
S
E
S
H
R
G
Zebra Danio
Brachydanio rerio
NP_001153567
1022
117847
I566
H
A
D
S
I
S
S
I
D
S
T
N
K
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137610
1364
155352
H886
E
S
E
E
A
T
D
H
E
V
N
L
N
M
A
Honey Bee
Apis mellifera
XP_001121004
1135
129725
T665
G
S
S
D
E
E
D
T
I
D
N
N
T
V
Q
Nematode Worm
Caenorhab. elegans
NP_494939
1427
163517
D956
W
K
Q
M
L
E
S
D
E
A
T
M
G
Y
E
Sea Urchin
Strong. purpuratus
XP_784455
790
90080
L398
D
R
S
S
V
P
R
L
P
W
H
D
I
A
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
K576
V
Q
R
W
N
H
S
K
R
N
K
A
P
N
E
Baker's Yeast
Sacchar. cerevisiae
P36126
1683
195185
G810
D
E
T
F
A
F
I
G
G
T
D
L
C
Y
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.7
97.8
91
N.A.
91
90.6
N.A.
22
79.4
75.6
66.6
N.A.
34.8
40.3
35.9
35.1
Protein Similarity:
100
92
99
95.1
N.A.
95.6
95.6
N.A.
24.8
88.8
86.3
78.3
N.A.
50.9
57.7
51
49.5
P-Site Identity:
100
13.3
93.3
66.6
N.A.
93.3
86.6
N.A.
0
20
20
13.3
N.A.
6.6
0
26.6
6.6
P-Site Similarity:
100
20
93.3
73.3
N.A.
93.3
86.6
N.A.
0
33.3
26.6
20
N.A.
13.3
13.3
40
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.6
21
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.6
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
13
0
0
0
0
7
0
7
0
7
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% C
% Asp:
13
0
19
7
0
0
13
7
19
7
7
7
0
0
0
% D
% Glu:
7
7
7
7
7
13
0
0
38
7
38
0
0
0
13
% E
% Phe:
13
0
0
44
0
7
0
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
7
7
0
0
0
44
0
25
% G
% His:
13
0
0
0
13
13
0
13
0
0
7
0
7
0
0
% H
% Ile:
0
0
0
0
13
0
7
19
7
0
0
0
7
0
0
% I
% Lys:
0
38
0
0
0
0
0
7
7
0
7
0
7
0
0
% K
% Leu:
25
0
32
0
13
0
7
7
0
0
0
13
0
32
0
% L
% Met:
0
0
7
7
0
0
0
0
0
0
0
7
0
7
0
% M
% Asn:
7
0
0
0
7
0
0
0
0
7
13
13
13
7
0
% N
% Pro:
0
0
0
0
0
32
0
0
7
0
0
0
7
0
7
% P
% Gln:
0
7
7
0
0
0
0
0
0
0
0
38
0
0
7
% Q
% Arg:
0
13
7
0
19
0
7
0
7
0
0
0
0
7
0
% R
% Ser:
0
13
13
25
0
25
63
32
7
50
7
13
0
13
0
% S
% Thr:
0
0
7
0
0
7
0
7
0
7
19
0
7
7
25
% T
% Val:
7
0
0
0
13
0
0
0
0
7
0
0
0
7
0
% V
% Trp:
7
0
0
7
0
0
0
0
0
7
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _